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Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2- dependent transcription of Ifng

NIAID Data Ecosystem2026-05-02 收录

细胞免疫调控

免疫治疗机制

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE237643 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2024-09-11

细胞免疫调控

滤泡淋巴瘤微环境

Fibroblastic reticular cells (FRCs) are the specialized lymphoid stromal cells initially identified as triggering T-cell recruitment and dynamic motion in secondary lymphoid organs. Interestingly, FRC

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β 1 -Adrenoceptor Autoantibodies from DCM Patients Enhance the Proliferation of T Lymphocytes through the β 1 -AR/cAMP/PKA and p38 MAPK Pathways

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BackgroundAutoantibodies against the second extracellular loop of the β1-adrenergic receptor (β1-AA) not only contribute to increased susceptibility to heart failure, but also play a causative role in

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Efficacious anti-CTLA-4 antibodies drive myeloid activation and TME reprograming through FcγR engagement and Type-I interferon signaling

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单细胞RNA测序

Despite the clinical success of checkpoints inhibitors, a significant gap still exists in our understanding of their in vivo mechanism of action, thus limiting the rational development of next generat

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Macrophage function in tissue repair and remodeling requires IL-4/IL-13 with apoptotic cells. Macrophage function in tissue repair and remodeling requires IL-4/IL-13 with apoptotic cells

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细胞凋亡机制

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

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Impact of dieldrin on transcription in Jurkat T cells

毒液转录组学

细胞免疫调控

Dieldrin is a pesticide with a suspected impact on chromatin. Here, we have exposed Jurkat cells to dieldrin for 30 min. and examined by next generation sequencing the impact on transcription. This im

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Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2- dependent transcription of Ifng

资源简介：

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