five

Crystal structure of mouse CARM1 in complex with inhibitor LH1427

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Protein Data Bank Japan2025-12-10 更新2026-03-21 收录
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Crystal structure of mouse CARM1 in complex with inhibitor LH1427 Descriptor: 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, 4-[2-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methylamino]ethylamino]-1-(methoxymethyl)pyrimidin-2-one, ... Authors: Cura, V, Marechal, N, Troffer-Charlier, N, Halby, L, Arimondo, P, Bonnefond, L, Cavarelli, J. Deposit date: 2016-09-12 Release date: 2017-09-20 Last modified: 2025-12-10 Method: X-RAY DIFFRACTION (2.294 Å) Cite: Hijacking DNA methyltransferase transition state analogues to produce chemical scaffolds for PRMT inhibitors. Philos.Trans.R.Soc.Lond.B Biol.Sci., 373, 2018
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2016-09-12
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