Engineered Lactobacillus paracasei 3×pBD1/ΔHLJ-27 as a Novel Antibiotic Alternative: Dual Efficacy in Promoting Animal Growth and Suppressing Salmonella Infection via Immune Activation

Fig.1 Effects of oral administration of recombinant strains on the growth performance of BALB/c mice. Fig.2 Efficacy of oral recombinant strain against intestinal S. typhimurium infection in mice. Fig.3. Capability of intestinal colonization and growth-enhancing effects of recombinant strain 3×pBD1/ΔHLJ-27 in piglets. Fig.4 The recombinant strain 3×pBD1/ΔHLJ-27 mitigates illness symptoms and facilitates intestinal barrier restoration in infected piglets. Fig. 5. The changes of intestinal microbial diversities in piglets with oral administration of 3×pBD1/ΔHLJ-27. Fig.6. Immunological responses in piglets treated with 3×pBD1/ΔHLJ-27, pPG/ΔHLJ-27, or challenged with S. typhimurium were assessed.