Relationship Between Real World Evidence Publications and Entresto Sales

This dataset assesses the relationship between the cadence of RWE publications and sales of sacubitril/valsartan (Entresto®) following launch. The data reveal that an additional RWE-related publication was associated with an estimated mean increase in quarterly sales of $1.8M (from quarter q to q+1 following publication), $3.5M (from q+1 to q+2), and $2.7M (from q+2 to q+3). In adjusted models, an additional RWE publication was associated with a mean gain in sales from quarter q+1 to q+2 of $2.6M. RWE publications were not associated with an increase in sales in the quarter following publication, and the association was attenuated by third quarter following publication.