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Global mapping of estrogen receptor and histone modifications in breast tumor samples uncovers distinct patterns for aromatase inhibitor resistance

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NIAID Data Ecosystem2026-03-11 收录
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ChIP-seq on primary breast cancer tumor samples for Era, H3K4me3, H3K27me3. Patients had a poor or good outcome after aromatase inhibitor treatment. Differential binding patterns between good and poor outcome patients were identified for each marker, predicting response to treatment Overall design: comparing ER, H3K4me3 and H3K27me3 patterns between two breast cancer patient populations

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2019-09-23
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