Structural annotation verses codon usage.

The table shows the median p> values among structural and non-structural genes, under the aqua and orange randomization tests. Small p> values indicate significantly elevated CAI, controlling for the amino acid sequence (aqua test) and the GC3 sequence (orange test). We also report the significance of non-parametric ANOVAs that compare median p>-values between the structural and non-structural genes. Analyses are limited to those genes that pass the aqua test, as described in the main text; similar results are found without this restriction.