scPII Benchmarking Results
收藏Zenodo2026-02-02 更新2026-05-26 收录
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https://zenodo.org/doi/10.5281/zenodo.17713781
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资源简介：
Contains all the benchmarking results performed on 16 CCLE scRNA-seq pan-cancer datasets according to the following benchmarking schemes -
Testing 4 GRNS construction algorithms (Pearson, Spearman, GRNBoost2, pcNet) to evaluate the performance of scPII.
Testing explained variance cutoff for optimal performance of scPII with GRNBoost2-derived GRNs.
Testing runtimes and accuracy of scPII against virtual KO algorithms (GenKI and scTenifoldKnk) in 3 CCLE scRNA-seq cell lines.
File naming convention
CCLE_Benchmark -
scPII summary files - {algorithm}_{CellLine}_{InteractionCutOff}_{ProportionOfExplainedVariance}_scPII_Summary.csv
Median gene KO effect of top 50 genes by algorithm - {algorithm}_GeneKOEffect_{InteractionCutOff}_{ProportionOfExplainedVariance}_Medians_P.csv
VirtualKO_Benchmark -
scRNA-seq-derived-GRN used for benchmarking - {CellLine}_{algorithm}_GRN.npz
Summary files for each algorithm - {CellLine}_{algorithm}_Summary.csv
Compiled scores from three algorithms - {CellLine}_Benchmark_Data.csv
提供机构：
Zenodo
创建时间：
2026-02-02
