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Structure of human RIPK3-MLKL complex

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Protein Data Bank Japan2024-11-20 更新2026-04-19 收录
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Structure of human RIPK3-MLKL complex Descriptor: Mixed lineage kinase domain-like protein, N-[4-({2-[(cyclopropanecarbonyl)amino]pyridin-4-yl}oxy)-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide, Receptor-interacting serine/threonine-protein kinase 3 Authors: Meng, Y, Davies, K.A, Czabotar, P.E, Murphy, J.M. Deposit date: 2021-05-03 Release date: 2021-11-17 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.23 Å) Cite: Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis. Nat Commun, 12, 2021

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2021-05-03
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