首页/数据集/Supplementary File S1 from Targeting CDK4/6 Represents a Therapeutic Vulnerability in Acquired BRAF/MEK Inhibitor–Resistant Melanoma

Supplementary File S1 from Targeting CDK4/6 Represents a Therapeutic Vulnerability in Acquired BRAF/MEK Inhibitor–Resistant Melanoma

NIAID Data Ecosystem2026-04-29 收录

黑色素瘤耐药性

肿瘤治疗基因组学

数据链接：

https://figshare.com/articles/dataset/Supplementary_File_S1_from_Targeting_CDK4_6_Represents_a_Therapeutic_Vulnerability_in_Acquired_BRAF_MEK_Inhibitor_Resistant_Melanoma/22521678 数据链接链接失效反馈

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资源简介：

WES MB1998 and MB2132

应用场景：

创建时间：

2021-10-01

癌症预后分子标志物

肿瘤治疗基因组学

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FOXD1 Promotes Dedifferentiation and Vemurafenib-resistance in Melanoma by Regulating the Expression of CTGF

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FOXD1基因调控

Metastatic melanoma is the most aggressive skin cancer and associated with a poor prognosis. Targeted therapy is one of the most important treatments for patients with BRAFV600E-mutated advanced melan

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Honokiol Bis-Dichloroacetate (Honokiol DCA) Demonstrates Activity in Vemurafenib-Resistant Melanoma in Vivo.

黑色素瘤耐药性

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The majority of human melanomas bears BRAF mutations and thus is treated with inhibitors of BRAF, such as vemurafenib. While patients with BRAF mutations often demonstrate an initial dramatic response

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Gene expression profiling of oncogenic NRAS driven mouse melanomas that have developed resistance to NRAS withdrawal

黑色素瘤耐药性

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Targeted therapies have the potential to revolutionize cancer care by providing personalized treatment strategies that are less toxic and more effective but it is clear that for most solid tumors supp

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Data_Sheet_1_Pharmacological STING Activation Is a Potential Alternative to Overcome Drug-Resistance in Melanoma.pdf

黑色素瘤耐药性

STING信号通路

Melanoma is the most aggressive type of skin cancer and resistance to the conventional chemotherapy is the major cause for its poor prognosis. Metabolic perturbations leading to increased production o

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Supplementary File S1 from Targeting CDK4/6 Represents a Therapeutic Vulnerability in Acquired BRAF/MEK Inhibitor–Resistant Melanoma

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