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Killing of Staphylococcus aureus by C-8-Methoxy Fluoroquinolones

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PubMed Central2026-05-16 收录
下载链接:
https://pmc.ncbi.nlm.nih.gov/articles/PMC105579/
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资源简介:
C-8-methoxy fluoroquinolones were more lethal than C-8-bromine, C-8-ethoxy, and C-8-H derivatives for Staphylococcus aureus, especially when topoisomerase IV was resistant. The methoxy group also increased lethality against wild-type cells when protein synthesis was inhibited. These properties encourage refinement of C-8-methoxy fluoroquinolones to kill staphylococci.
提供机构:
American Society for Microbiology (ASM)
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