CRYSTAL STRUCTURE OF B-RAF IN COMPLEX WITH BI 882370
收藏Protein Data Bank Japan2024-01-10 更新2026-03-21 收录
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https://pdbj.org/mine/summary/5csx
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CRYSTAL STRUCTURE OF B-RAF IN COMPLEX WITH BI 882370 Descriptor: N-(3-{5-[(1-ethylpiperidin-4-yl)(methyl)amino]-3-(pyrimidin-5-yl)-1H-pyrrolo[3,2-b]pyridin-1-yl}-2,4-difluorophenyl)propane-1-sulfonamide, Serine/threonine-protein kinase B-raf, alpha-D-glucopyranose Authors: Bader, G, Stadtmuller, H, Steurer, S. Deposit date: 2015-07-23 Release date: 2016-03-09 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.51 Å) Cite: A Novel RAF Kinase Inhibitor with DFG-Out-Binding Mode: High Efficacy in BRAF-Mutant Tumor Xenograft Models in the Absence of Normal Tissue Hyperproliferation. Mol.Cancer Ther., 15, 2016
创建时间：
2015-07-23
