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BACE-1 in complex with HEA-type macrocyclic inhibitor, MV078571

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Protein Data Bank Japan2024-10-09 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4gmi
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BACE-1 in complex with HEA-type macrocyclic inhibitor, MV078571 Descriptor: (4S,8E)-4-[(1R)-2-{[2-(5-tert-butyl-1,3-oxazol-2-yl)propan-2-yl]amino}-1-hydroxyethyl]-16-methyl-6-oxa-3-azabicyclo[12.3.1]octadeca-1(18),8,14,16-tetraene-2,13-dione, ACETATE ION, Beta-secretase 1, ... Authors: Lindberg, J.D, Derbyshire, D. Deposit date: 2012-08-16 Release date: 2013-09-04 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Design and synthesis of novel BACE-1 inhibitors To be Published
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2012-08-16
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