AD-affiliated genes

List of the 499 genes found to be associated with Alzheimer's disease in the MalaCards database. The following description is taken directly from the database. The genes list is composed by taking into account: i) The GeneCards search mechanism, ii) Genetic testing resources supplying specific genetic tests for the disease, iii) Genetic variations resources supplying specific causative variations in genes for the disease and iv) Resources that manually curate the association of the disease with genes. A prioritizing algorithm is applied to generate the genes list. The table shows gene symbols, descriptions, relevance scores, and the context according to which the gene is related to the disease. The relevance score is computed by factoring the importance of the different resources associating the gene with the disease.MalaCards "elite" genes (marked with *) are those likely to be associated with causing the disease, since their gene-disease associations are supported by manually curated and trustworthy sources.