BP_Prior v2.11.0

BioPAX (BP) Prior s a tool for people who work with proteomics data and want to conduct pathway-context aware analysis. Given a set of annotated protein states, (such as phosphorylations, active/inactive tags and concentration levels), this programs creates a map from the input states onto the Pathway Commons 2 entities and finds the minimum distance between them -- the distances are extracted from BioPAX graphs. The ouput, so called prior information network, is a tab-limited file in Simple Interaction Format and it contains: - Source/target entities - Directional distance measure between these two entities - Pubmed IDs associated with links as external references - Reactions and their types included in the path between two entities.