Acox2
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ENCODES a protein that exhibits 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity; fatty acid binding; flavin adenine dinucleotide binding; INVOLVED IN fatty acid beta-oxidation; fatty acid metabolic process; bile acid biosynthetic process (ortholog); PARTICIPATES IN bile acid biosynthetic pathway; cerebrotendinous xanthomatosis pathway; congenital bile acid synthesis defect pathway; ASSOCIATED WITH congenital bile acid synthesis defect 6 (ortholog); Experimental Liver Cirrhosis (ortholog); Pyruvate Dehydrogenase E1-Beta Deficiency (ortholog); FOUND IN peroxisome; cytosol (ortholog); intracellular membrane-bounded organelle (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol
编码一种具有3alpha,7alpha,12alpha-三羟基-5beta-胆固醇酰辅酶A 24-羟化酶活性的蛋白质;参与脂肪酸结合;黄素腺嘌呤二核苷酸结合;涉及脂肪酸β-氧化;脂肪酸代谢过程;胆汁酸生物合成过程(同源);参与胆汁酸生物合成途径;参与 cerebrotendinous xanthomatosis 途径;参与先天性胆汁酸合成缺陷途径;与先天性胆汁酸合成缺陷6(同源)相关;与实验性肝硬变(同源)相关;与丙酮酸脱氢酶E1-Beta缺乏(同源)相关;存在于过氧化物酶体;细胞质(同源);细胞内膜包裹的细胞器(同源);与(+)-schisandrin B;1-萘基异氰酸酯;17beta-雌二醇相互作用。
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