Mass spectrometry data profiling whole cell lipid extractions from Mycobacterium tuberculosis H37Rv and strains mutated in Rv3377c and Rv3378c

Mass spectrometry data files of whole cell lipid extracts from strains of Mycobacterium tuberculosis with engineered replacement of the gene(s) Rv3377c, Rv3378c, or both, as well as the non-mutated parental strain H36Rv.  Biological quadruplicate samples from each strain were profiled to assess terpene nucleoside biosynthesis.  These data were analyzed in the manuscript, “Mycobacteria that cause tuberculosis have retained ancestrally acquired genes for the biosynthesis of chemically diverse terpene nucleosides” (https://doi.org/10.1371/journal.pbio.3002813) and were included in analyzed form (DOI 10.5281/zenodo.8096634). Mass spectrometry data is provided as centroided mzXML files, along with an annotated sample list and instrument metadata.