Recent Advances in High-Throughput Automated Powder Dispensing Platforms for Pharmaceutical Applications

A wide array of pharmaceutical research
studies involve dispensing
a variety of powders such as active ingredients, intermediates, catalysts,
and formulation excipients. Automated powder dispensing platforms
are increasingly relied upon to perform the mundane task of filling
vials in multi-well plates for high-throughput experimentation workflows.
A small group of pharmaceutical scientists collaborated to evaluate
recent advances in commercially available automation platforms from
two instrument manufacturers using previously reported objective and
systematic testing protocols. This manuscript details the testing
conditions used for the evaluation and the results obtained and assesses
the impact that the powder characteristics had on the performance
of the selected platforms through statistical analysis.