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Seven functional classes of proteins we studied are found to be not significantly distinguished in their folded topology.

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Figshare2015-12-02 更新2026-04-29 收录
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The shared folds between each functional class of proteins and their complement are not significantly small compared to what happens with random chances, with a one-tailed p-value greater than 0.05 in every case, suggesting that these cellular proteins are highly connected in structural fold space.

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2015-12-02
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