REA, restriction enzyme-based assay; PSQ, pyrosequencing; AS-PCR, allele-specific PCR with DPO primer; other Abbreviations as in Table 1.*, calculated from the number of patients having at least one m
BackgroundMyelodysplastic neoplasms (MDS) are a clonal hematopoietic stem cell disease with an increased risk of progression to acute myeloid leukemia (AML). Cytogenetic abnormalities, mainly aneuploi
We developed 3'-TARGET-seq, a single-cell genotyping and RNA-seq method, which allows accurate detection of multiple mutations within single-cells from genomic and coding DNA in parallel with high thr
