DHFR:NADP+:FOL complex (crystal 2, pass 5, 295 K)
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DHFR:NADP+:FOL complex (crystal 2, pass 5, 295 K) Descriptor: Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... Authors: Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. Deposit date: 2022-09-12 Release date: 2023-09-20 Last modified: 2026-02-18 Method: X-RAY DIFFRACTION (1.19 Å) Cite: Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Proc.Natl.Acad.Sci.USA, 121, 2024
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2022-09-12
