Crystal structure of human TRF1 TRFH domain in complex with compound 17

Crystal structure of human TRF1 TRFH domain in complex with compound 17 Descriptor: (3R)-3-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]piperidine, DIMETHYL SULFOXIDE, GLYCEROL, ... Authors: Casale, G, Le Bihan, Y.-V, van Montfort, R.L.M, Guettler, S. Deposit date: 2024-11-15 Release date: 2025-11-26 Last modified: 2025-12-03 Method: X-RAY DIFFRACTION (2.44 Å) Cite: Discovery of first-in-class inhibitors of the TRF1:TIN2 protein:protein interaction by fragment screening. Sci Rep, 15, 2025