The list of 17 adjacent codon pairs identified by [39] to have inhibitory effects on the translation efficiency in yeast. The direction is from 5′ to 3′.
Test for association of codon optimality with mRNA decay rate, protein abundance per mRNA, and ribosome occupancy. (A) Spearman’s correlation and partial correlation coefficients to assess association
Recent studies have suggested that the thermodynamic stability of mRNA secondary structure near the start codon can regulate translation efficiency in Escherichia coli, and that translation is more ef
The uneven use of synonymous codons in the transcriptome regulates the efficiency and fidelity of protein translation rates. Yet, the importance of this codon bias on regulating cell state-specific ex
Additional file 5. CUSTOM-optimized fluorescent variants. (A) Relative Codon Usage of optimized protein variants. (B) Sequences of optimized protein variants. (C) Targeted proteomics of GFP and mCherr