BRD4 bromodomain 2 in complex with gamma-carboline-containing compound, number 18.

BRD4 bromodomain 2 in complex with gamma-carboline-containing compound, number 18. Descriptor: 1,2-ETHANEDIOL, 1-(3-cyclopropyl-5-methyl-1H-pyrazol-4-yl)-7-(3,5-dimethyl-1,2-oxazol-4-yl)-8-methoxy-5H-pyrido[4,3-b]indole, Bromodomain-containing protein 4 Authors: Meagher, J.L, Stuckey, J.A. Deposit date: 2015-04-09 Release date: 2015-07-01 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.27 Å) Cite: Structure-Based Design of gamma-Carboline Analogues as Potent and Specific BET Bromodomain Inhibitors. J.Med.Chem., 58, 2015