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Distinct chromatin states enhance multilineage function in HSC subsets that drive improved thymic reconstitution

Figshare2025-07-05 更新2026-04-28 收录

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https://figshare.com/articles/dataset/Distinct_chromatin_states_enhance_multilineage_function_in_HSC_subsets_that_drive_improved_thymic_reconstitution/28899050 数据链接链接失效反馈

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Raw western blot images related Supplemental Figure 8A

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2025-07-05

造血干细胞表观遗传

化疗应激响应

Purpose: The goals of this study are to elucidate the underlying mechanism for the regulation of HSC divisions. Methods: Before or after wild type (WT) mice were treated with 5-fluorouracil (5-FU), 15

NIAID Data Ecosystem70

Sca-1 is an early-response target of histone deacetylase inhibitors and marks hematopoietic cells with enhanced function

造血干细胞表观遗传

组蛋白去乙酰化抑制剂作用机制

Expression profiles of LSK cells stimulated for 24h in the presence or in the absence of of valproic acid (VPA) The molecular process that underlies the biological effects of valproic acid (VPA), a wi

NIAID Data Ecosystem30

Additional file 8 of Metformin promotes female germline stem cell proliferation by upregulating Gata-binding protein 2 with histone β-hydroxybutyrylation

造血干细胞表观遗传

ChIP-qPCR引物设计

Additional file 8. Table S3. Sequence of primers used in ChIP-qPCR

Figshare2023-05-26 更新00

Define roles of JMJD1B in mediating histone demethylation and gene expression

组蛋白甲基化功能

造血干细胞表观遗传

The arginine or lysine methylation status of histones dynamically changes during many essential cellular processes, particularly during embryonic and hematopoietic stem cell development. The enzymes d

NIAID Data Ecosystem50

Genome wide chromatin accessibility of Helios null hematopoietic stem and progenitor cells. Genome wide chromatin accessibility of Helios null hematopoietic stem and progenitor cells

染色质可及性分析

造血干细胞表观遗传

This experiment aimed to determine Helios contribution in chromatin accessibility in hematopoietic stem and progenitor cells. Thus, we examined the change in chromatin accessibility in purified hemato

NIAID Data Ecosystem10

Distinct chromatin states enhance multilineage function in HSC subsets that drive improved thymic reconstitution

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