Human topoisomerase IIbeta in complex with DNA and etoposide
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Human topoisomerase IIbeta in complex with DNA and etoposide Descriptor: (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), ... Authors: Wu, C.C, Li, T.K, Farh, L, Lin, L.Y, Lin, T.S, Yu, Y.J, Yen, T.J, Chiang, C.W, Chan, N.L. Deposit date: 2011-03-01 Release date: 2011-07-06 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.162 Å) Cite: Structural basis of type II topoisomerase inhibition by the anticancer drug etoposide Science, 333, 2011
创建时间：
2011-03-01
