Crystal structure of human STING in complex with MD1193
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Crystal structure of human STING in complex with MD1193 Descriptor: 9-[(1R,6R,8R,13E,15R,17R,18R)-17-(6-aminopurin-9-yl)-9,18-bis(fluoranyl)-3,12-bis(oxidanyl)-3,12-bis(oxidanylidene)-2,4,7,11,16-pentaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.3.0.0^{6,10}]octadec-13-en-8-yl]purin-6-amine, Stimulator of interferon genes protein Authors: Smola, M, Klima, M, Boura, E. Deposit date: 2021-11-10 Release date: 2022-10-19 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.359 Å) Cite: Vinylphosphonate-based cyclic dinucleotides enhance STING-mediated cancer immunotherapy. Eur.J.Med.Chem., 259, 2023
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2021-11-10
