Nucleotides difference in <i>hemagglutinin</i> (HA3) genes identified by RPM v.1 from 250 influenza A/H3N2 isolates.

Note: * Amino acid (aa) and nucleotide (nt) positions correspond to the “prototype sequence” for hemagglutinin of influenza A/H3N2 (HA3) on RPM v.1; the number in the parenthesis correspond to the position of full length HA3 sequence, & amino acid and its corresponding codon at each position were separated by “/”. SNPs relative to the prototype sequence are underlined. The numbers in column 4, 6, and 8 indicate the number of samples containing the amino acid substitution; #HA3 prototype sequence was derived from A/Fujian/411/02 strain. A/New York/258/2005 (California-lineage) and A/Aichi/133/2005 (Wellington-lineage) represent two major groups identified from all isolates. The one outlier was identified as A/Wyoming/3/03 (with IS)-like isolate.