RNA-seq differential expression results for E10.5 PKN2 cardiomyocyte-specific knockout embryonic mouse hearts

DescriptionThis dataset contains gene-level differential expression results from bulk RNA-sequencing of embryonic day 10.5 (E10.5) mouse hearts comparing cardiomyocyte-specific Pkn2 conditional knockout (cKO) and littermate control embryos. RNA-seq libraries were generated from ventricular tissue and analyzed using the DESeq2 pipeline. Differential expression was calculated between control and cKO samples.The table includes normalized expression values for each biological replicate together with statistical metrics from the differential expression analysis.Column descriptionsRow.names – Gene symbol.baseMean – Mean normalized expression across all samples calculated by DESeq2.log2FoldChange – Log2 fold change of gene expression in PKN2 cardiomyocyte knockout (cKO) hearts relative to control hearts.lfcSE – Standard error of the log2 fold change estimate.stat – Wald test statistic from the DESeq2 differential expression analysis.pvalue – Raw p-value for differential expression between cKO and control samples.padj – Benjamini–Hochberg adjusted p-value (false discovery rate).CT1 – Normalized expression value for control biological replicate 1.CT2 – Normalized expression value for control biological replicate 2.CT3 – Normalized expression value for control biological replicate 3.CT4 – Normalized expression value for control biological replicate 4.KO1 – Normalized expression value for PKN2 cKO biological replicate 1.KO2 – Normalized expression value for PKN2 cKO biological replicate 2.KO3 – Normalized expression value for PKN2 cKO biological replicate 3.KO4 – Normalized expression value for PKN2 cKO biological replicate 4.sig – Direction of significant change (Up, Down, or not significant) based on the statistical thresholds used in the study.