Crystal structure of BRAF/MEK complex with NST-628 and inactive RAF
收藏Protein Data Bank Japan2024-07-10 更新2026-04-19 收录
下载链接：
https://pdbj.org/mine/summary/9axy
下载链接
链接失效反馈官方服务：
资源简介：
Crystal structure of BRAF/MEK complex with NST-628 and inactive RAF Descriptor: Dual specificity mitogen-activated protein kinase kinase 1, MAGNESIUM ION, N-[3-fluoro-4-({7-[(3-fluoropyridin-2-yl)oxy]-4-methyl-2-oxo-2H-1-benzopyran-3-yl}methyl)pyridin-2-yl]-N'-methylsulfuric diamide, ... Authors: Quade, B, Huang, X. Deposit date: 2024-03-06 Release date: 2024-04-17 Last modified: 2024-07-10 Method: X-RAY DIFFRACTION (3.6 Å) Cite: The Pan-RAF-MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS-MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers. Cancer Discov, 14, 2024
创建时间：
2024-03-06
