Comparison of group difference and age effect on metabolite concentration in white matter and thalamus.

Age corrected mean and standard error (SE) are presented for each group, mean absolute concentrations [mM] are presented above the aqueous fraction concentrations [mM]AQ. 95% confidence intervals of the mean difference between the groups are also presented. Significant effects are emphasized in bold. Mixed linear model of ‘Age’, and ‘Group’ are presented with estimate of linear regression coefficient β and standard error (SE).*P**P***PResults of the age effect are given in mM/year and mMAQ/year for the absolute concentrations and the aqueous fraction concentrations respectively. Nctrl (Number of Controls), Nneg (Number of Non-lesional MS patients) , Npos (Number of lesional MS patients).