Crystal structure of MerTK in complex with a type 1.5 aminopyridine inhibitor
收藏Protein Data Bank Japan2024-01-31 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/7aaz
下载链接
链接失效反馈官方服务：
资源简介：
Crystal structure of MerTK in complex with a type 1.5 aminopyridine inhibitor Descriptor: 1,2-ETHANEDIOL, 2-azanyl-~{N}-[(1~{S},2~{S})-2-[[4-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]phenyl]methoxy]cyclopentyl]-5-(1-methylpyrazol-4-yl)pyridine-3-carboxamide, CHLORIDE ION, ... Authors: Pflug, A, Schimpl, M, McCoull, W, Nissink, J.W.M, Overman, R.C, Rawlins, P.B, Truman, C, Underwood, E, Warwicker, J, Winter-Holt, J. Deposit date: 2020-09-05 Release date: 2020-11-04 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.855 Å) Cite: A-loop interactions in Mer tyrosine kinase give rise to inhibitors with two-step mechanism and long residence time of binding. Biochem.J., 477, 2020
创建时间：
2020-09-05
