Intracellular Na elevation in the heart is a hallmark of pathologies where both acute and chronic metabolic remodeling occurs. We assessed whether acute (75μM ouabain 100nM blebbistatin) and chronic m
Purpose: Observing the response of the heart to dietary interventation at the metabolomic and transcriptomic level may have relevance for cardiovascular diseases Methods: RNA Seq of 12 week old WT mal
Doxorubicin-induced cardiomyopathy (DOX-CM) is a severe complication of doxorubicin (DOX) chemotherapy. Characterized by cumulative and irreversible myocardial damage, its pathogenesis has not been fu
