five

Simian immunodeficiency virus Genome sequencing and assembly

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https://www.ncbi.nlm.nih.gov/sra/SRP073659
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These sequences refer to those described in our manuscript, "Vaccination with Live Attenuated Simian Immunodeficiency Virus (SIV) Protects from Mucosal, but not Necessarily Intravenous, Challenge with a Minimally Heterologous SIV". Here, there were three animals who had been immunized with a live attenuated SIV and then challenged with a pathogenic SIV containing different sequences. These three animals developed high viremia after this challenge. We sequenced the replicating virus to determine if it was a recombinant of the live attenuated SIV and the challenge virus.
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2017-11-21
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