ChagasDB

Chagas disease is a parasitical disease caused by Trypanosoma cruzi which affects ∼7 million people worldwide. Per year, ∼10 000 people die from this pathology. Indeed, ∼30% of humans develop severe chronic forms, including cardiac, digestive or neurological disorders, for which there is still no treatment. In order to facilitate research on Chagas disease, a manual curation of all papers corresponding to 'Chagas disease' referenced on PubMed has been performed.查加斯病（Chagas disease）是由克氏锥虫（Trypanosoma cruzi）引发的寄生虫病，全球约700万人受其影响。每年约有1万人死于该疾病。事实上，约30%的感染者会发展为严重慢性病症，涵盖心脏、消化或神经系统紊乱，目前针对此类病症仍无有效治疗方案。为助力查加斯病相关研究，研究人员对PubMed数据库中收录的全部与“查加斯病”相关的文献进行了人工审校整理。

搜集汇总

背景与挑战

背景概述

ChagasDB是一个手动整理的数据库，汇集了PubMed中与克氏锥虫感染相关的分子数据，包括基因、蛋白质和多态性等。该数据库旨在通过提供简化访问来促进查加斯病的研究，并支持搜索和下载功能，以帮助理解疾病并寻找治疗方法。