A distinct subset of stem-cell memory is poised for the cytotoxicity program in CD4+ T cells in humans

NIAID Data Ecosystem2026-05-02 收录

免疫细胞分化

T细胞毒性功能

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE288989 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2025-08-27

SMAD4 impedes conversion of NK cells into ILC1-like cells by curtailing non-canonical TGFb signaling (mouse data sets). Mus musculus

免疫细胞分化

TGFb信号通路

Among the features that distinguish type 1 innate lymphoid cells (ILC1s) from NK cells is a gene signature indicative of TGFb-family cytokine imprinting. To assess the impact of TGFb family cytokines

NIAID Data Ecosystem70

BLUEPRINT RNA-seq of Epigenetic programming during monocyte to macrophage differentiation and trained innate immunity

免疫细胞分化

表观遗传调控

Monocyte differentiation into macrophages represents a cornerstone process for host defense. Concomitantly, immunological imprinting of either tolerance or trained immunity determines the functional f

NIAID Data Ecosystem40

Cxcr3+ CD62L+ effector CD8+ T cells function as precursor of central memory cells

免疫细胞分化

表观遗传调控

We report the application of single-molecule-based sequencing technology for high-throughput profiling of histone modifications in mammalian cells. By obtaining over four billion bases of sequence fro

NIAID Data Ecosystem30

Innate sensor Dhx9 directly binds to multiple genes related to effector CD8 T cell differentiation [ChIP-Seq]

免疫细胞分化

ChIP-seq基因靶点分析

We provide a set of genes that are directly bound by Dhx9 in CD8 T cells from LCMV infected mice. Examination of binding peaks in genome of wt GP33+CD8 T cells from the spleens 8 days post infection

NIAID Data Ecosystem60

Additional file 7 of Single-cell transcriptomics highlights immunological dysregulations of monocytes in the pathobiology of COPD

单细胞转录组学

免疫细胞分化

Additional file 7: Dataset 5. Genes dynamically expressed during CD14+ classical monocyte-to-CD14+ intermediate monocyte differentiation, related to Fig. S3M and S3N, in which the top 250 genes based

Figshare2022-12-20 更新40

A distinct subset of stem-cell memory is poised for the cytotoxicity program in CD4+ T cells in humans

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