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Mesenchymal Nuclear factor I B regulates cell proliferation and epithelial differentiation during lung maturation

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE24465
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We generated Nfibf/f mice and then cross with Dermo1-Cre mice to obtain Nfibf/f, Dermo1-Cre mice. In these Nfibf/f, Dermo1-Cre mice, there are defects in sacculation and epithelial cell differentiation. We performed micoarray analysis to find the genes which are possibley regulated by NFI-B and related to lung maturation during lung development. We used microarrays to performing transcriptional profiling of Nfibf/f, Dermo1-Cre and Nfibf/f lungs at E18.5
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2019-08-28
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