Global circadian transcript profile of mouse liver entrained by inverted feeding

Circadian clocks in peripheral organs are entrained by feeding. Eating in the right time is crucial to maintain metabolic health, whereas eating in the wrong time increases the susceptibility to metabolic diseases. It is unknown how change of mealtime impacts circadian transcriptomes in peripheral organs and brain, such as liver, heart, kidney and visceral adipose tissue. Here, we presented global circadian transcript profile of mouse liver entrained by inverted feeding to compile an atlas for mechanistic insights into how feed-fast cycle regulates circadian biology. ncRNA-seq of coding and non-coding transcriptome in liver collected from daytime-restricted feeding (DRF) or nighttime-restricted feeding (NRF, reference), totaling 280 samples