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Crystal structure of the fifth immunoglobulin domain (Ig5) of human Robo1 in complex with the mutant scFv fragment (P103A) of murine monoclonal antibody B5209B

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Protein Data Bank Japan2024-10-30 更新2026-03-21 收录
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Crystal structure of the fifth immunoglobulin domain (Ig5) of human Robo1 in complex with the mutant scFv fragment (P103A) of murine monoclonal antibody B5209B Descriptor: Heavy chain of the anti-human Robo1 antibody B5209B scFv, Light chain region of the anti-human Robo1 antibody B5209B scFv, Roundabout homolog 1, ... Authors: Mizohata, E, Nakayama, T, Kado, Y, Yokota, Y, Inoue, T. Deposit date: 2018-07-02 Release date: 2019-01-30 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.31 Å) Cite: Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface. Structure, 27, 2019

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2018-07-02
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