Anti-cancer activity of ST101, a novel antagonist of CCAAT/enhancer binding protein β
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE213013
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To investigate the impact of ST101 on transcriptional activity of C/EBPβ protein, U251, A549 and MCF7 tumor cell lines were exposed to 10µM ST101 for 24 hours. Gene expression profiling analysis demonstrates attenuation of C/EBPβ target gene transcriptions, including a significant decrease in expression of survival, transcription factors and cell cycle-related proteins. Comparative gene expression profiling analysis of RNA-Seq data for U251, A549 and MCF7 cells. Triplicate samples of cells were either treated with ST101 or vehicle.
创建时间:
2023-01-13



