CD95 suppresses immune infiltration in a model of triple negative breast cancer
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE154682
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CD95 acts as an immune suppressor for TNBC tumors when grown in syngeneic mice. 4T1 cells were grown in two mouse strains. Comparisons included parental, a pool stably expressing vCas9 and two clones in which CD95/Fas was deleted using CRISPR-Cas9 gene editing, clone #54 and clone #69. Examination of differential gene mRNA expression in tumor with and without CD95 expression in NSG or Balb/c mice.
创建时间:
2022-09-08



