One-shot analysis of translated mammalian lncRNAs with AHARIBO
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下载链接：
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA692822
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资源简介：
AHARIBO, a method for the detection of lncRNAs either untranslated, but associated with ribosomes, or encoding small peptides. Using AHARIBO in mouse embryonicstem cells during neuronal differentiation, we isolated ribosome-protected RNA fragments, translated RNAs and corresponding de novo synthesized polypeptides. Besides identifying mRNAs under active translation and associated ribosomes, we found and distinguished lncRNAs acting as ribosome sponges or encoding micropeptides, laying the ground for a better functional understanding of hundreds lncRNAs.
创建时间：
2021-01-18
