Naïve sensitivity of diagnostic tests estimated in those who had blood culture positive for O. tsutsugamushi, had a combination of PCR assays positive or had an eschar.

Data are sensitivity (n positive).* IFA IgM was defined as positive in those with either admission IFA IgM titre of ≥1: 12,800 or at least a four-fold rise in convalescence IFA IgM titre compared to the admission IFA IgM titre.** A combination of PCR assays was defined as positive when at least two out of the three PCR assays (56kDa PCR assay, 47kDa-based real-time PCR assay and groEL-based real-time PCR assays) were positive.Naïve sensitivity of diagnostic tests estimated in those who had blood culture positive for O. tsutsugamushi, had a combination of PCR assays positive or had an eschar.