Studies on the Nitroreductase Prodrug-Activating System. Crystal Structures of the Enzyme Active Form and Complexes with the Inhibitor Dicoumarol and Dinitrobenzamide Prodrugs

Studies on the Nitroreductase Prodrug-Activating System. Crystal Structures of the Enzyme Active Form and Complexes with the Inhibitor Dicoumarol and Dinitrobenzamide Prodrugs Descriptor: FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NAD(P)H nitroreductase Authors: Johansson, E, Parkinson, G.N, Denny, W.A, Neidle, S. Deposit date: 2003-03-03 Release date: 2003-04-08 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Studies on the Nitroreductase Prodrug-Activating System. Crystal Structures of Complexes with the Inhibitor Dicoumarol and Dinitrobenzamide Prodrugs and of the Enzyme Active Form J.Med.Chem., 46, 2003