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REG3A promotes the development of pancreatic cancer by activating EGFR pathway

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE282763
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REG3A is highly expressed in pancreatic tissues, but its significance is unclear. We found that REG3A overexpressed in paracancerous acinar cells interacted with EGFR on tumor cells to stimulate downstream tumor growth signals and promote the occurrence and development of tumors Wild-type PANC1 cells and OE-REG3a-transfected PANC1 cells were used for 3v3 RNA-seq
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2025-02-26
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