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Curcuminoids Suppress EV-D68 Infection via the CRYAB-RBM26 Axis by Reversing Viral Hijacking of Nucleic Acid Metabolism and Activating IFN Pathways

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This study demonstrates that curcuminoids exert antiviral effects by upregulating CRYAB, which in turn stabilizes RBM26-mediated nucleic acid metabolism pathways. Additionally, CRYAB contributes to the maintenance of the interferon protein pool, leading to the activation of IFN-dependent antiviral pathways.

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2025-08-06
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