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circZFR promote lung carcinogenesis and oxidative phosphorylation by modulating alternative splicing

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE193064
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Our study suggested that circZFR was a potential oncogene in lung adenocarcinoma. To investigate the function of circZFR, we performed high-thoughput RNA sequencing (RNA-Seq) assays after the silence of circZFR in A549 cell lines. In human lung adenocarcinoma A549 cells, we downregulated the expression of circZFR utilizing small interference RNA (siRNA) and used scrumble as negative control. Then we used RNA-Seq to reveal the change of mRNA profiles after the silence of circZFR.
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2023-09-12
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