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Association of SNPs rs1801274 (FCGR2A) and rs396991 (FCGR3A) with HIV status.

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Figshare2015-12-02 更新2026-04-29 收录
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https://figshare.com/articles/dataset/_Association_of_SNPs_rs1801274_FCGR2A_and_rs396991_FCGR3A_with_HIV_status_/481509
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Significant differences related to HIV status are shown. For FCGR3A, carriage of V allele was associated with increased risk of HIV seropositivity. Among HIV sero-positive cases, there was a significant association between VV genotype (i.e., lack of allele F) and the progressor phenotype. For the FCGR2A∶FCGR3A extended haplotype, the RR∶FF genotype was associated with disease progression.Fisher's exact test (2-tailed) p values and Odds ratios are listed where significant.*None of the NVS donors carried the F allele, so odds ratio were not calculated.#Include Progressors and NVS.**Not significant.
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2015-12-02
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