Triptolide sensitizes cancer cells to nucleoside DNA methyltransferase inhibitors through inhibition of DCTPP1 mediated cell-intrinsic resistance [Array]. Triptolide sensitizes cancer cells to nucleoside DNA methyltransferase inhibitors through inhibition of DCTPP1 mediated cell-intrinsic resistance [Array]
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA769734
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We show that high DCTPP1 expression was associated with cell-intrinsic resistance to nucleoside DNMT inhibition, and that triptolide and its analogs could overcome this resistance. Overall design: mRNA profiles of DU145 treated with the DNMT inhibitor decitabine alone or in combination with triptolide
创建时间：
2021-10-08
