Kidney disease development is poorly understood due to the complex cellular interactions of more than 25 different cell types, each with specialized functions. Here, we used single cell RNA-sequencing
The aim of this study is to explore the effects of L. casei Zhang on renal injury we orally gavaged male C57BL/6 mice with or without L. casei Zhang (Lac.z) for 4 weeks (1×10^9 CFU per day) prior to b
Mis-sense mutations of Inverted Formin 2 (INF2) are among the most common causes of genetic FSGS with or without Charcot-Marie-Tooth (CMT) disease. Here, we extracted glomeruli from Heterozygous INF2
Tubulointerstitial Transcriptome in the Neptune Cohort Tubulointerstitial Transcriptome ----------------------------------------- Raw data (fastq) files are available upon approved ancillary study req
Proteinuria is pathogenic to proximal tubular cells (PTC) and linked with progression to renal failure. Angiotensin II (AngII) is also independently involved in the pathogenesis of progressive renal i
