Mass spectrometry analysis of protein changes induced by UBE2D/eff knockdown in Drosophila skeletal muscle, and their rescue by co-expression of human UBE2D2.

Tandem mass tag (TMT) mass spectrometry identifies protein changes induced in skeletal muscle by eff RNAi (compared to control interventions) and their rescue by co-expression of hUBE2D2 (the human homolog of eff). A dedicated tab reports the modulation of proteasome levels by UBE2D/effRNAi. Related to Figs 5 and 6. (XLSX)